Posts Tagged ‘molecular glues’
Exploring the Landscape of Molecular Glues: A Promising Frontier in Therapeutics
Introduction Advancements in molecular biology have paved the way for innovative therapeutic approaches, particularly in the field of monovalent degraders and molecular glues. These areas have gained significant attention and investment, offering promising solutions for previously challenging diseases. In this blog, we summarize key insights shared by Rachel East, TPD Research Analyst, and Frank Plowden,…Read more
Read MorePaper: Unveiling Molecular Glue-like Degraders: CRISPR Screen Reveals Promising Pathway
Summary of research paper: CRISPR Screen Reveals BRD2/4 Molecular Glue-like Degrader via Recruitment of DCAF16 Study Authors: Andrea G. Shergalis, Violeta L. Marin, David Y. Rhee, Sameera Senaweera, Rebecca L. McCloud, Judith A. Ronau, Charles W. Hutchins, Shaun McLoughlin, Kevin R. Woller, Scott E. Warder, Anil Vasudevan, and Justin M. Reitsma. Molecular glues (MGs) are…Read more
Read MoreUnraveling the Power of Molecular Glues | TPD Searchlight Journal Club
The Targeted Protein Degradation Searchlight network’s launches it’s new Journal Club, where the network delve into the latest research and advancements in the field. In this edition, the network will be focusing on the fascinating realm of molecular glues and their role in targeted protein degradation. Our esteemed moderator, William Farnaby from the University of…Read more
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